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csn [2017-8-11 16:0:3]
function
chitin degradation
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.27|Utilization of other polymeric carbohydrates][category|SW 6|Groups of genes] → [category|SW 6.12|Secreted proteins]Gene
Coordinates
2,747,984 → 2,748,817
The protein
Catalyzed reaction/ biological activity
Endohydrolysis of beta-(1→4)-linkages between D-glucosamine residues in a partly acetylated chitosan (according to Swiss-Prot)Protein family
glycosyl hydrolase 46 family (according to Swiss-Prot)Structure
[PDB|4OLT] (from Pseudomonas sp. 39% identity) [pubmed|24766439][SW|Localization]
extracellular (signal peptide), major constituent of the secretome [Pubmed|18957862]Expression and Regulation
Operons
genes
[gene|EDE47BF726A4D2F0A4E1D9481C97576650339F84|csn]
description
[pubmed|22383849]
regulatory mechanism
[protein|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB]: repression, [pubmed|20817675], in [regulon|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB regulon]view in new tabBiological materials
Mutant
MGNA-A240 (csn::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/240 NBRP B. subtilis, Japan]References
11065371,18957862,22031025,20817675,12401130,24766439